Principles of Bioinorganic Chemisry

human carbonic anhydrase
biomineralization of mesoporous silica shell mimetics: morphogenesis of shapes (from: Adv. Mater. 1997, 9, 662)


I. Introduction:  Definitions, Scope, Aims
II.     Principles of Coordination Chemistry
(transition metal complexes, bioligands, structures)
III. Transport Phenomena A: Uptake, Transport, and Assembly of Metals
(cell membrane, ion-specific channels and pores, iron metabolism, ion pumps)
IV. Transport Phenomena B: Uptake and Transport of Small Molecules
(dioxygen transport, hemoglobin, myoglobin, hemerythrin, hemocyanin)
V. Transport Phenomena C: Electron Transfer Proteins
(electron carriers, cytochromes, blue copper proteins, iron-sulfur proteins)
VI. Metal Ion Folding and Cross-Linking of Biomolecules
(zinc finger, regulatory role of calcium, catalytic RNA molecules)
VII. Metalloenzymes in Acid–Base Catalysis
(carboxypeptidase, carbonic anhydrase, alcohol dehydrogenase)
VIII. Metalloenzymes in Redox Catalysis
(OEC= oxygen-evolving complex, cytochrom P-450, vitamin B12, nitrogenases)
IX. Biomineralization
X. Metals in Medicine


Textbooks on Bioinorganic Chemistry

...further comprehensive references

  • D. F. Shriver, P. W. Atkins, C. H. Langford, Inorganic Chemistry  (J. Heck, W. Kaim, M. Weidenbruch, Herausg.), 3. Aufl., Wiley-VCH, Weinheim (1999).  EUR 54.10.
  • J. E. Huheey, E. A. Keiter, R. L. Keiter, Inorganic Chemistry (R. Steudel, Herausg.), 2. Aufl., Walter de Gruyter, Berlin-New York (1995). EUR 78.-.
  • I. Bertini, H. B. Gray, S. J, Lippard, J. S. Valentine, Bioinorganic Chemistry, University Science Books, Mill Valley (1994). $ 72.- + tax).
  • W. Kaim und B. Schwederski, Bioanorganische Chemie.  Zur Funktion chemischer Elemente in Lebensprozessen.  2. Aufl., Teubner (1995). EUR 29.-.
  • S. J. Lippard und J. M. Berg, Bioanorganische Chemie.  Spektrum Akademischer Verlag, Heidelberg (1995).  Preis ca. EUR 79.30.
  • J. A. Cowan, Inorganic Biochemistry - An Introduction. 2. Aufl., WILEY-VCH (1997). EUR 109.-. 
  • S. Mann, Chem. unserer Zeit1986, 20, 69-76. 
  • S. Mann, J. Webb und R. J. P. Williams, Biomineralization: chemical and biochemical perspectives. VCH, Weinheim (1989).
  • Collection of essays: Science1993, 261, 699-730